SCHEMBL7061707

SCHEMBL7061707

CCOc1ccc(OC(=O)C(=O)OC)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.54
KMT2A Q03164 3/20 0.53
CYP1A2 P05177 2/20 0.53
MEN1 O00255 2/20 0.53
PLK1 P53350 1/20 0.53
POLB P06746 1/20 0.53
LMNA P02545 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
PARP10 Q53GL7 1/20 0.52
ALDH1A1 P00352 3/20 0.51
MAPT P10636 3/20 0.49
NPC1 O15118 3/20 0.49
KDM4E B2RXH2 2/20 0.49
HTT P42858 1/20 0.49
MAPK1 P28482 1/20 0.49
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27853482 0.92 NQO1 (0.64) NQO1KMT2ACYP1A2MEN1PLK1
SCHEMBL77123 0.81 TP53 (0.59) CYP1A2LMNANPC1SMN1; SMN2
SCHEMBL8518384 0.81 TP53 (0.59) CYP1A2LMNANPC1SMN1; SMN2
SCHEMBL7061682 0.81 RAB9A (0.54) KMT2AMEN1PLK1POLBLMNA
SCHEMBL3419802 0.79 NQO1 (0.64) NQO1KMT2ACYP1A2MEN1PLK1
SCHEMBL7065322 0.79 CA1 (0.54) KMT2ACYP1A2PLK1LMNAPARP10
SCHEMBL452749 0.79 ELANE (0.56) NQO1KMT2ACYP1A2MEN1PLK1
SCHEMBL9668859 0.78 NQO1 (0.61) NQO1KMT2ACYP1A2MEN1PLK1
SCHEMBL7166940 0.78 NQO1 (0.61) NQO1KMT2ACYP1A2MEN1PLK1
SCHEMBL7063122 0.78 LMNA (0.59) KMT2ACYP1A2LMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013633-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2003-05-28 EP disclosed
EP-0795539-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2001-10-31 EP disclosed
EP-0814074-B1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES (JP) 2001-03-28 EP disclosed
EP-1013633-A1 Process for producing a diaryl carbonate Ube Industries, Ltd. (JP) 2000-06-28 EP disclosed
US-5811573-A Process for producing a diaryl carnonate UBE INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
US-5731453-A Process for producing a diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0814074-A1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES, LTD. (JP) 1997-12-29 EP disclosed
EP-0795539-A1 Process for producing a diaryl carbonate UBE INDUSTRIES LIMITED (JP) 1997-09-17 EP disclosed