SCHEMBL7065322

SCHEMBL7065322

COC(=O)C(=O)Oc1ccc(OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.54
CA2 P00918 7/20 0.54
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
HTT P42858 3/20 0.52
ALDH1A1 P00352 2/20 0.52
GAA P10253 2/20 0.52
PLK1 P53350 1/20 0.50
CA12 O43570 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
LMNA P02545 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
PARP1 P09874 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7061292 0.93 CES2 (0.58) CA1CA2CES2CES1SMN1; SMN2
SCHEMBL7063122 0.84 LMNA (0.59) CA1CA2NPC1RAB9AHTT
SCHEMBL28711125 0.84 KDM4E (0.55) SMN1; SMN2NPC1RAB9AALDH1A1LMNA
SCHEMBL7063314 0.83 HPGD (0.50) SMN1; SMN2HTTALDH1A1LMNACYP1A2
SCHEMBL6202766 0.83 HPGD (0.66) CA1CA2CES2CES1SMN1; SMN2
SCHEMBL5605891 0.82 ALDH1A1 (0.47) SMN1; SMN2RAB9AHTTALDH1A1GAA
SCHEMBL6618980 0.82 CES2 (0.52) CA1CA2CES2CES1SMN1; SMN2
SCHEMBL8662363 0.82 CA1 (0.56) CA1CA2CES2CES1SMN1; SMN2
SCHEMBL8465124 0.80 CES2 (0.50) CA1CA2CES2CES1SMN1; SMN2
SCHEMBL10030775 0.80 KDM4E (0.46) SMN1; SMN2HTTALDH1A1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013633-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2003-05-28 EP disclosed
EP-0795539-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2001-10-31 EP disclosed
EP-0814074-B1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES (JP) 2001-03-28 EP disclosed
EP-1013633-A1 Process for producing a diaryl carbonate Ube Industries, Ltd. (JP) 2000-06-28 EP disclosed
US-6018072-A SUBJECTING AN ALKYLARYL OXALATE TO A DISPROPORTIONATION REACTION IN THE PRESENCE OF A DISPROPORTIONATION CATALYST TO PRODUCE A DIARYL OXALATE WHILE REMOVING A DIALKYL OXALATE BY-PRODUCT UBE INDUSTRIES, LTD. (JP) 2000-01-25 US disclosed
US-5731453-A Process for producing a diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0814074-A1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES, LTD. (JP) 1997-12-29 EP disclosed
EP-0795539-A1 Process for producing a diaryl carbonate UBE INDUSTRIES LIMITED (JP) 1997-09-17 EP disclosed