Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672689 | 0.98 | NAAA (0.51) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL1595662 | 0.86 | NAAA (0.61) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL1695751 | 0.86 | NAAA (0.61) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL183236 | 0.86 | NAAA (0.61) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| Hydrochloric Acid SCHEMBL22466282 | 0.84 | NAAA (0.59) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL7905393 | 0.84 | NAAA (0.59) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL9577043 | 0.84 | NAAA (0.59) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL97374 | 0.84 | NAAA (0.60) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL949697 | 0.83 | CYP2C19 (0.47) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL949533 | 0.83 | CYP2C19 (0.47) | NAAAEPHX1HTTCYP2C19CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298090-A1 | Modulators of ROR-gamma Receptors, Composition and Use Thereof | KULING THERAPEUTICS (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-11-20 | — | — | US | disclosed |
| US-6586368-B1 | Benzofuran derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298090-A1 | Modulators of ROR-gamma Receptors, Composition and Use Thereof | RORC, RORB, RORA | NAAA 4441/4885EPHX1 1472/4885HTT 4553/4885 |
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | CBR3, CBR1, HAAO | NAAA 367/4885EPHX1 236/4885HTT 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.