Metolachor

Metolachor

SCHEMBL7062329

CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.COc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(F)(F)F)nc(C(F)(F)F)n1.O=C(O)C1=NOC(c2ccccc2)(c2ccccc2)C1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metolachor SCHEMBL7058151 0.90 MAPT (0.40) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Metolachor SCHEMBL7059338 0.84 MAPT (0.35) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL14655539 0.83 MAPT (0.37) MAPTALDH1A1MEN1KMT2AKDM4E
Metolachor SCHEMBL7059321 0.81 MAPT (0.33) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Foramsulfuron SCHEMBL7053909 0.78 CDK1 (0.52) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Metolachor SCHEMBL7057714 0.70 MEN1 (0.38) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL53993 0.70 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL30116869 0.70 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL29508588 0.70 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL6829101 0.70 MAPT (0.44) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242421-A1 Herbicidal composition SYNGENTA CROP PROTECTION, INC. 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242421-A1 Herbicidal composition MSRB3, MTX1, MTX2 MAPT 4031/4885ALDH1A1 639/4885MEN1 2329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.