Metolachor

Metolachor

SCHEMBL7059338

C=CCN(CC=C)C(=O)C(Cl)Cl.CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.COc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(F)(F)F)nc(C(F)(F)F)n1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metolachor SCHEMBL7058151 0.92 MAPT (0.40) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Dichlormid SCHEMBL14655513 0.84 RAB9A (0.39) MAPTALDH1A1KDM4ENPC1
Metolachor SCHEMBL7062329 0.84 MAPT (0.34) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Metolachor SCHEMBL7059321 0.82 MAPT (0.33) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Foramsulfuron SCHEMBL7060560 0.76 CDK1 (0.55) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL30116869 0.72 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL29508588 0.72 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL53993 0.72 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL6829101 0.71 MAPT (0.44) MAPTALDH1A1MEN1KMT2AKDM4E
Prosulfuron SCHEMBL19462957 0.69 THRB (0.47) MAPTALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242421-A1 Herbicidal composition SYNGENTA CROP PROTECTION, INC. 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242421-A1 Herbicidal composition MSRB3, MTX1, MTX2 MAPT 4031/4885ALDH1A1 639/4885MEN1 2329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.