Metolachor

Metolachor

SCHEMBL7059321

CC1COc2ccccc2N1C(=O)C(Cl)Cl.CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.COc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(F)(F)F)nc(C(F)(F)F)n1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metolachor SCHEMBL7058151 0.87 MAPT (0.40) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2
Benoxacor SCHEMBL14655536 0.85 ALDH1A1 (0.36) MAPTMEN1ALDH1A1KMT2A
Metolachor SCHEMBL7059338 0.82 MAPT (0.35) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2
Metolachor SCHEMBL7062329 0.81 MAPT (0.34) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2
Metolachor SCHEMBL8145298 0.80 MEN1 (0.45) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2
Foramsulfuron SCHEMBL7055801 0.79 CDK1 (0.49) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2
Metolachor SCHEMBL7059993 0.73 MEN1 (0.36) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2
Sulfentrazone SCHEMBL7579765 0.72 PPOX (0.44) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2
Sulfentrazone SCHEMBL7576546 0.70 PPOX (0.37) MAPT
Fomesafen SCHEMBL7586818 0.70 MEN1 (0.36) MAPTMEN1ALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242421-A1 Herbicidal composition SYNGENTA CROP PROTECTION, INC. 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242421-A1 Herbicidal composition MSRB3, MTX1, MTX2 MAPT 4031/4885MEN1 2329/4885ALDH1A1 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.