SCHEMBL7062463

SCHEMBL7062463

CC(c1ccc(Cl)cc1)N1CCC1C(=O)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.46
FKBP1A P62942 10/20 0.46
GPBAR1 Q8TDU6 2/20 0.42
STS P08842 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064400 0.92 FKBP1A (0.50) FKBP1A
SCHEMBL7066507 0.90 FKBP1A (0.47) FKBP1A
SCHEMBL7067284 0.89 FKBP1A (0.51) FKBP1ASLC6A3
SCHEMBL7066355 0.88 FKBP1A (0.47) FKBP1A
SCHEMBL7067269 0.86 GPBAR1 (0.40) FKBP1AGPBAR1
SCHEMBL7064598 0.85 FKBP1A (0.43) CCR1FKBP1ASLC6A3
SCHEMBL7066103 0.84 ALDH1A1 (0.48) MEN1KMT2A
SCHEMBL7068101 0.82 SLC6A2 (0.46) CCR1SLC6A2SLC6A4SLC6A3
SCHEMBL7067276 0.81 OPRM1 (0.43) FKBP1ASLC6A2SLC6A4SLC6A3
SCHEMBL7067185 0.80 TSHR (0.58) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed