Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067280 | 0.90 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2TSHRPOLBKMT2A | |
| SCHEMBL7067156 | 0.88 | FKBP1A (0.44) | ALDH1A1SMN1; SMN2TSHRPOLBMEN1 | |
| SCHEMBL7062112 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL7065723 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TSHRMAPTMAPK1 | |
| SCHEMBL7066432 | 0.86 | FKBP1A (0.43) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6232174 | 0.85 | TSHR (0.58) | SMN1; SMN2TSHRHSD11B1 | |
| SCHEMBL6231109 | 0.85 | TSHR (0.58) | SMN1; SMN2TSHRHSD11B1 | |
| SCHEMBL7067185 | 0.85 | TSHR (0.58) | SMN1; SMN2TSHRHSD11B1 | |
| SCHEMBL7062463 | 0.84 | CCR1 (0.46) | MEN1KMT2A | |
| SCHEMBL7066127 | 0.84 | TSHR (0.46) | SMN1; SMN2TSHRPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |