Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 4/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944315 | 0.80 | L3MBTL1 (0.36) | ADH1CADH1AMAPK1NPSR1L3MBTL1 | |
| SCHEMBL14920073 | 0.75 | ALDH1A1 (0.42) | EPHX2NAAAADH1CADH1ACYP1A2 | |
| SCHEMBL9871113 | 0.75 | PHGDH (0.40) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL1835532 | 0.74 | EPHX2 (0.42) | EPHX2NAAAMAPTMAPK1NPSR1 | |
| SCHEMBL1835393 | 0.73 | NAAA (0.42) | EPHX2NAAAMAPK1EPHX1 | |
| SCHEMBL1838391 | 0.73 | NAAA (0.42) | EPHX2NAAAMAPK1EPHX1 | |
| SCHEMBL1838299 | 0.73 | NAAA (0.42) | EPHX2NAAAMAPK1EPHX1 | |
| SCHEMBL18092158 | 0.73 | NAAA (0.42) | EPHX2NAAAMAPK1EPHX1 | |
| SCHEMBL28177806 | 0.72 | NAAA (0.41) | EPHX2NAAAEPHX1 | |
| SCHEMBL27925979 | 0.72 | NAAA (0.42) | EPHX2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023897-A1 | Methods for preventing or treating disease mediated by toxin-secreting bacteria | SEER PHARMACEUTICALS | 2004-02-05 | — | — | US | disclosed |
| WO-2003041710-A1 | METHODS FOR PREVENTING OR TREATING DISEASE MEDIATEB BY TOXIN-SECRETING BACTERIA | SEER PHARMACEUTICALS, LLC (US) | 2003-05-22 | — | — | WO | disclosed |
| US-5225601-A | Sulfur containing compounds for skin disorders | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |