Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19697329 | 0.84 | RAB9A (0.52) | ESRRAMAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7045055 | 0.82 | MRGPRX4 (0.51) | ESRRAMRGPRX4SMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL3151750 | 0.81 | AR (0.44) | ESRRAMRGPRX4KMT2AALDH1A1LMNA | |
| SCHEMBL6061341 | 0.80 | ACHE (0.47) | MAPTRAB9AMRGPRX4KMT2AALDH1A1 | |
| SCHEMBL11173052 | 0.78 | TDP1 (0.49) | ESRRAHPGDMRGPRX4SMN1; SMN2KMT2A | |
| SCHEMBL25490777 | 0.78 | MRGPRX4 (0.45) | MRGPRX4SMN1; SMN2ALDH1A1KDM4ECYP2A6 | |
| SCHEMBL7131209 | 0.78 | CYP2A6 (0.44) | ESRRAMRGPRX4SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7149236 | 0.75 | HTT (0.40) | ESRRAMRGPRX4KDM4EL3MBTL1 | |
| SCHEMBL903435 | 0.75 | MAPT (0.83) | ESRRAMAPTRAB9AHPGDMAOB | |
| SCHEMBL9999838 | 0.75 | MAPT (0.83) | ESRRAMAPTRAB9AHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003031382-A2 | PROCESS FOR THE PREPARATION OF HYDROXYDIPHENYL ETHER COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (NL) | 2003-04-17 | — | — | WO | disclosed |