SCHEMBL7149236

SCHEMBL7149236

Cc1ccc(C(C)(C)C)c(Oc2cc[c]cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
AR P10275 7/20 0.38
KDM4E B2RXH2 2/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
ACHE P22303 1/20 0.33
ESRRA P11474 2/20 0.33
CYP2C9 P11712 1/20 0.33
SLC6A4 P31645 3/20 0.32
HTR2A P28223 2/20 0.32
KCNH2 Q12809 2/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25490777 0.83 MRGPRX4 (0.45) HTTL3MBTL1ARKDM4EMRGPRX4
SCHEMBL6061341 0.81 ACHE (0.47) HTTL3MBTL1ARKDM4EMRGPRX4
SCHEMBL3151750 0.80 AR (0.44) HTTL3MBTL1ARKDM4EMRGPRX4
SCHEMBL922844 0.79 TSHR (0.41) HTTARACHECYP2C9SLC6A4
SCHEMBL28942882 0.78 HTT (0.45) HTTL3MBTL1ARKDM4EMRGPRX4
SCHEMBL8569226 0.77 EZH2 (0.40) HTTL3MBTL1KDM4E
SCHEMBL7131209 0.76 CYP2A6 (0.44) HTTL3MBTL1ARKDM4EMRGPRX4
SCHEMBL920577 0.75 GAA (0.41) L3MBTL1ARACHESLC6A4HTR2A
SCHEMBL7063003 0.75 ESRRA (0.61) L3MBTL1KDM4EMRGPRX4ESRRA
SCHEMBL10001985 0.74 AR (0.44) ARACHEESRRACYP2C9SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORP. 2003-04-10 US disclosed
EP-1246602-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS Ciba SC Holding AG (CH) 2002-10-09 EP disclosed
WO-2001051013-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CUTA, MGLL, TMEM205 HTT 1398/4885L3MBTL1 1744/4885AR 4495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.