Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169868 | 0.88 | IKBKB (0.47) | PARP1IKBKBMKNK1MKNK2BCAT2 | |
| SCHEMBL29374101 | 0.88 | IKBKB (0.47) | PARP1IKBKBMKNK1MKNK2BCAT2 | |
| SCHEMBL27919911 | 0.81 | MAP4K4 (0.50) | PARP1HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL8949874 | 0.81 | DHODH (0.46) | CYP2C9IKBKBCYP1A2CYP2D6CYP2C19 | |
| Urea SCHEMBL28406941 | 0.79 | HSD17B1 (0.68) | PARP1HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL1789847 | 0.78 | BCAT2 (0.67) | PARP1HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL4151580 | 0.77 | BCAT2 (0.59) | PARP1CYP3A4IKBKBCYP2C19BCAT2 | |
| SCHEMBL17292699 | 0.77 | BRD4 (0.51) | PARP1MKNK1MKNK2ALDH1A1 | |
| SCHEMBL7064896 | 0.75 | ESR1 (0.43) | PARP1HSD17B1ESR1ESR2ALDH1A1 | |
| SCHEMBL10701680 | 0.75 | CHEK1 (0.47) | HSD17B1IKBKBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608163-B2 | From bisphenol A and a hydroxyphenyl-substituted terephthalimide; improved resistance to dilute caustic solution; use in automatic dishwater parts | GENERAL ELECTRIC COMPANY | 2003-08-19 | — | — | US | claimed |
| US-6608163-B2 | From bisphenol A and a hydroxyphenyl-substituted terephthalimide; improved resistance to dilute caustic solution; use in automatic dishwater parts | GENERAL ELECTRIC COMPANY | 2003-08-19 | — | — | US | disclosed |