Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689821 | 0.78 | EP300 (0.49) | TSHRSMN1; SMN2NR3C1PGRNR3C2 | |
| SCHEMBL13268412 | 0.77 | TSHR (0.58) | TSHRSMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL30659708 | 0.76 | KEAP1 (0.55) | TSHRNR3C1PGRNR3C2AR | |
| SCHEMBL2303211 | 0.75 | TSHR (0.61) | TSHRSMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL6671258 | 0.74 | TSHR (0.59) | TSHRSMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL8026971 | 0.74 | HTR6 (0.68) | TSHRSMN1; SMN2NR3C1PGRNR3C2 | |
| SCHEMBL2068498 | 0.73 | KEAP1 (0.65) | TSHRNR3C1PGRNR3C2AR | |
| SCHEMBL29904739 | 0.73 | KEAP1 (0.65) | TSHRNR3C1PGRNR3C2AR | |
| SCHEMBL892273 | 0.73 | KEAP1 (0.52) | TSHRSMN1; SMN2NR3C1PGRNR3C2 | |
| SCHEMBL1127421 | 0.73 | CA2 (0.62) | KEAP1L3MBTL1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198505-B1 | CARBONATE POLYMER COMPOSITIONS STABILIZED AGAINST DISCOLORATION AND PHYSICAL PROPERTY DETERIORATION DURING STERILIZATION BY IONIZING RADIATION | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-01-07 | — | — | EP | disclosed |
| EP-1198505-A1 | CARBONATE POLYMER COMPOSITIONS STABILIZED AGAINST DISCOLORATION AND PHYSICAL PROPERTY DETERIORATION DURING STERILIZATION BY IONIZING RADIATION | THE DOW CHEMICAL COMPANY (US) | 2002-04-24 | — | — | EP | disclosed |
| US-6166116-A | Carbonate polymer compositions stabilized against discoloration and physical property deterioration during sterilization by ionizing radiation | THE DOW CHEMICAL COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000075223-A1 | CARBONATE POLYMER COMPOSITIONS STABILIZED AGAINST DISCOLORATION AND PHYSICAL PROPERTY DETERIORATION DURING STERILIZATION BY IONIZING RADIATION | THE DOW CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |