SCHEMBL892273

SCHEMBL892273

CS(=O)(=O)Nc1ccccc1S(=O)(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KMT2A Q03164 2/20 0.50
EP300 Q09472 1/20 0.49
KAT2B Q92831 1/20 0.49
KAT8 Q9H7Z6 1/20 0.49
NFE2L2 Q16236 1/20 0.48
GAA P10253 1/20 0.47
NR3C1 P04150 1/20 0.46
PGR P06401 1/20 0.46
NR3C2 P08235 1/20 0.46
AR P10275 1/20 0.46
TSHR P16473 1/20 0.44
TTR P02766 1/20 0.44
FABP4 P15090 1/20 0.44
CCNA2 P20248 1/20 0.44
CDK2 P24941 1/20 0.44
MAPK14 Q16539 1/20 0.44
KDM4E B2RXH2 4/20 0.43
HPGD P15428 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5403732 0.83 TTR (0.46) L3MBTL1GAATSHRTTRFABP4
SCHEMBL30659708 0.83 KEAP1 (0.55) KEAP1L3MBTL1KMT2AEP300KAT2B
SCHEMBL2068498 0.80 KEAP1 (0.65) KEAP1L3MBTL1KMT2AEP300KAT2B
SCHEMBL29904739 0.80 KEAP1 (0.65) KEAP1L3MBTL1KMT2AEP300KAT2B
SCHEMBL11477009 0.80 CA2 (0.47) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL1127421 0.80 CA2 (0.62) KEAP1L3MBTL1
SCHEMBL35949 0.79 HTR6 (0.60) L3MBTL1GAATSHRTTRFABP4
SCHEMBL14508939 0.78 KEAP1 (0.50) KEAP1L3MBTL1KMT2AEP300KAT2B
SCHEMBL141197 0.78 EP300 (0.65) KEAP1L3MBTL1KMT2AEP300KAT2B
Hydrochloric Acid SCHEMBL28173629 0.78 HTR6 (0.58) L3MBTL1GAATSHRTTRFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8657433-B2 Porphyrazine coloring matter, ink composition, recording method, and colored object NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-02-25 US disclosed
US-20120081457-A1 PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-04-05 US disclosed
US-20070006772-A1 Cyan dye for ink-jet NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070006772-A1 Cyan dye for ink-jet CRY1, SMO, RB1 KEAP1 212/4885L3MBTL1 1166/4885KMT2A 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.