Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397640 | 0.82 | SIGMAR1 (0.43) | SIGMAR1LMNAALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL4732903 | 0.70 | CA1 (0.42) | SIGMAR1LMNATP53ALDH1A1KDM4E | |
| SCHEMBL8859269 | 0.69 | CYP2D6 (0.37) | LMNAALDH1A1KDM4EGAACYP2C19 | |
| SCHEMBL7690874 | 0.68 | RAB9A (0.38) | SIGMAR1ALDH1A1CYP2C19CYP3A4HIF1A | |
| SCHEMBL16746581 | 0.67 | TSHR (0.44) | MIFALDH1A1TDP1CYP3A4CYP2D6 | |
| SCHEMBL16109798 | 0.67 | L3MBTL1 (0.40) | SIGMAR1MIFLMNAALDH1A1KDM4E | |
| SCHEMBL2339023 | 0.66 | PPARG (0.40) | LMNATP53ALDH1A1TDP1CYP3A4 | |
| SCHEMBL14967701 | 0.66 | SIGMAR1 (0.42) | SIGMAR1MIFLMNAALDH1A1KDM4E | |
| SCHEMBL16109506 | 0.65 | PPARG (0.44) | MIFLMNATP53ALDH1A1CYP1A2 | |
| SCHEMBL6376600 | 0.64 | PPARG (0.48) | LMNATP53ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083497-A1 | Taxoids, their preparation and pharmaceutical compositions containing them | AVENTIS PHARMA, S.A. | 2003-05-01 | — | — | US | disclosed |
| US-6384071-B2 | ANTITUMOR AGENTS | AVENTIS PHARMA, S.A. (FR) | 2002-05-07 | — | — | US | disclosed |
| US-20010021783-A1 | New taxoids, their preparation and pharmaceutical compositions containing them | Rhône-Poulenc Rorer S.A. | 2001-09-13 | — | — | US | disclosed |
| US-6194582-B1 | MULTI-DRUG RESISTANCE | RHONE-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083497-A1 | Taxoids, their preparation and pharmaceutical compositions containing them | TBXA2R, CBR1, CBR3 | SIGMAR1 926/4885MIF 4453/4885LMNA 3662/4885 |
| US-20010021783-A1 | New taxoids, their preparation and pharmaceutical compositions containing them | CBR1, TBXA2R, CBR3 | SIGMAR1 666/4885MIF 4325/4885LMNA 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.