Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065806 | 0.90 | NAMPT (0.36) | KDM4EALDH1A1CYP2D6PARP1MEN1 | |
| SCHEMBL7063010 | 0.81 | RBP4 (0.38) | ALDH1A1CYP2D6CYP2C19MAPTMEN1 | |
| SCHEMBL7612097 | 0.81 | KDM4E (0.38) | KDM4ETSHRGAAALDH1A1HTT | |
| SCHEMBL7612083 | 0.79 | KDM4E (0.36) | KDM4ETSHRGAAALDH1A1HTT | |
| SCHEMBL7065196 | 0.77 | NPC1 (0.32) | TSHRHPGD | |
| SCHEMBL6817245 | 0.77 | ALDH1A1 (0.39) | TSHRGAAALDH1A1HTTPOLB | |
| SCHEMBL7064160 | 0.75 | F2R (0.38) | KDM4EMAPTKMT2A | |
| SCHEMBL6194905 | 0.70 | ITGAL (0.46) | GAAALDH1A1POLBALK | |
| SCHEMBL7065799 | 0.66 | GPR183 (0.36) | KDM4EMEN1KMT2A | |
| SCHEMBL6918676 | 0.65 | ALDH1A1 (0.39) | KDM4EALDH1A1DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |