Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 4/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064158 | 0.81 | KDM4E (0.36) | MEN1ALDH1A1MAPTKMT2ACYP2D6 | |
| SCHEMBL7065196 | 0.80 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL27577333 | 0.79 | RBP4 (0.38) | RBP4LIPETRPV1GRM5NPC1 | |
| SCHEMBL6921386 | 0.75 | RAB9A (0.34) | TRPV1GRM5NPC1RAB9A | |
| SCHEMBL7065796 | 0.74 | UGT8 (0.32) | MEN1KMT2A | |
| SCHEMBL7063009 | 0.73 | ITGB2 (0.41) | — | |
| SCHEMBL7619039 | 0.70 | GRM5 (0.36) | GRM5NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL6919348 | 0.63 | SMN1; SMN2 (0.40) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL7646851 | 0.63 | AKR1C3 (0.42) | ALDH1A1HDAC4CYP2C19 | |
| SCHEMBL6921375 | 0.61 | HPGD (0.34) | NPC1RAB9AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |