⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321531 | 0.93 | FKBP5 (0.34) | — | |
| SCHEMBL290716 | 0.72 | OR51E2 (0.38) | — | |
| SCHEMBL7103933 | 0.71 | GRIA1 (0.56) | — | |
| SCHEMBL2044985 | 0.70 | — | — | |
| SCHEMBL15828532 | 0.68 | — | — | |
| SCHEMBL8621801 | 0.68 | MAPT (0.48) | — | |
| SCHEMBL4929162 | 0.65 | GRIA1 (0.55) | — | |
| SCHEMBL11826056 | 0.65 | PNMT (0.39) | — | |
| SCHEMBL6015897 | 0.65 | GRIA1 (0.53) | — | |
| SCHEMBL4937347 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12252473-B2 | Preparation methods of quinolone compounds and intermediates thereof | Chongqing University of Arts and Sciences (CN) | 2025-03-18 | — | — | US | claimed |
| US-20240400522-A1 | PREPARATION METHODS OF QUINOLONE COMPOUNDS AND INTERMEDIATES THEREOF | Chongqing University of Arts and Sciences (CN) | 2024-12-05 | — | — | US | claimed |
| WO-2023201780-A1 | METHOD FOR PREPARING QUINOLONE COMPOUND AND INTERMEDIATE THEREOF | 重庆文理学院 | 2023-10-26 | — | — | WO | claimed |
| CN-114702443-B | Process for preparing quinolone compounds and intermediates thereof | 重庆文理学院 | 2023-09-19 | — | — | CN | claimed |
| CN-114702443-A | Process for preparing quinolone compounds and intermediates thereof | 重庆文理学院 | 2022-07-05 | — | — | CN | claimed |
| EP-2336315-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | claimed |
| CN-104177363-A | Bicyclic heterocyclic amine Hedgehog signal pathway inhibitor | JIANGSU SIMCERE PHARMACEUTICAL | 2014-12-03 | — | — | CN | claimed |
| CN-104003990-A | Heterocyclic amine Hedgehog signal path inhibitor | JIANGSU SIMCERE PHARM RES CO | 2014-08-27 | — | — | CN | claimed |
| US-20140221420-A1 | CCR5 ANTAGONISTS FOR TREATING HIV | PURDUE RESEARCH FOUNDATION (US) | 2014-08-07 | — | — | US | claimed |
| CN-103864770-A | Pyrimidinamine and pyridinamine Hedgehog signal conduction inhibitors | JIANGSU SIMCERE PHARMACEUTICAL | 2014-06-18 | — | — | CN | claimed |
| EP-2547203-A1 | CCR5 MODULATORS FOR TREATING HIV | Purdue Research Foundation (US) | 2013-01-23 | — | — | EP | claimed |
| WO-2011116287-A1 | CCR5 MODULATORS FOR TREATING HIV | PURDUE RESEARCH FOUNDATION (US) | 2011-09-22 | — | — | WO | claimed |
| EP-2336315-A2 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-06-22 | — | — | EP | claimed |
| CN-1267334-A | Method for racemic biochemical resolusion of cis- and trans-pyrrolopiperidine | BAYER AG (DE) | 2000-09-20 | — | — | CN | claimed |
| EP-1003902-A1 | METHOD FOR RACEMIC BIOCHEMICAL RESOLUTION OF CIS- AND TRANS- PYRROLOPIPERIDINE | BAYER AG (DE) | 2000-05-31 | — | — | EP | claimed |
| WO-1999009200-A1 | METHOD FOR RACEMIC BIOCHEMICAL RESOLUTION OF CIS- AND TRANS- PYRROLOPIPERIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-25 | — | — | WO | claimed |
| US-12252473-B2 | Preparation methods of quinolone compounds and intermediates thereof | Chongqing University of Arts and Sciences (CN) | 2025-03-18 | — | — | US | disclosed |
| CN-119604304-A | Recombinant RNA molecules comprising an untranslated region or a segment encoding spike protein from the Severe acute respiratory coronavirus 2 Omikovia strain | 葛兰素史克生物有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-1999009200-A1 | METHOD FOR RACEMIC BIOCHEMICAL RESOLUTION OF CIS- AND TRANS- PYRROLOPIPERIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-25 | — | — | WO | disclosed |
| CN-1109877-A | One-pot process for the preparation of 3-quinolone carboxylic acid derivatives | BAYER AG (DE) | 1995-10-11 | — | — | CN | disclosed |