Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214214 | 0.83 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1TSHRLMNAHDAC3 | |
| SCHEMBL6919541 | 0.82 | HTT (0.41) | L3MBTL1ALDH1A1TSHRLMNAHDAC3 | |
| SCHEMBL6919885 | 0.77 | GAA (0.40) | MAPK1L3MBTL1ALDH1A1LMNAHDAC3 | |
| SCHEMBL6919835 | 0.77 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1TSHRLMNAHDAC3 | |
| SCHEMBL6919643 | 0.76 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1TSHRLMNAHDAC3 | |
| SCHEMBL6918282 | 0.73 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1TSHRLMNAHDAC3 | |
| SCHEMBL6922174 | 0.72 | MAPT (0.43) | MAPK1L3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL6919131 | 0.68 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1GAAMAPTHTT | |
| SCHEMBL6922367 | 0.68 | HTT (0.40) | L3MBTL1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL6921278 | 0.68 | TSHR (0.46) | MAPK1L3MBTL1ALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033431-A2 | HYDROXYPYRAZOLES FOR USE AGAINST METABOLIC-RELATED DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |