SCHEMBL28825873

SCHEMBL28825873

CC=C(C)C(=O)Oc1ccccc1CC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
L3MBTL1 Q9Y468 5/20 0.42
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PTGS2 P35354 2/20 0.37
HPGD P15428 1/20 0.37
ATM Q13315 1/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815627 0.86 THRA (0.57) THRATHRBPTGS2MTNR1AMTNR1B
SCHEMBL7064536 0.85 L3MBTL1 (0.50) THRATHRBL3MBTL1MAPTNPSR1
SCHEMBL16504636 0.85 KDM4E (0.42) MAPTTSHRHSD17B10PTGS2HPGD
SCHEMBL8755535 0.84 L3MBTL1 (0.46) THRATHRBL3MBTL1MAPTNPSR1
SCHEMBL7755391 0.83 THRA (0.44) THRATHRBL3MBTL1MAPTNPSR1
SCHEMBL147468 0.82 ELANE (0.47) THRATHRBL3MBTL1MAPTNPSR1
SCHEMBL7064539 0.80 L3MBTL1 (0.47) THRATHRBL3MBTL1MAPTNPSR1
SCHEMBL30850062 0.80 PTGS2 (0.55) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL68677 0.80 PTGS2 (0.55) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL28215669 0.79 ALDH1A1 (0.37) THRATHRBL3MBTL1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385044-B A kind of automobile safe airbag lid material TPV and preparation method thereof 嘉兴市博尔塑胶有限公司 2018-05-22 CN disclosed
CN-105385011-A TPV composition and automobile anti-collision strip Jiaxing boer plastic co ltd 2016-03-09 CN disclosed
CN-105385044-A TPV (Thermoplastic Vulcanizate) for automobile safety airbag cover material and preparation method for TPV Jiaxing boer plastic co ltd 2016-03-09 CN disclosed
CN-105367885-A Automotive air conditioning pipe material TPV ANHUI XIONGYA PLASTIC TECH CO LTD 2016-03-02 CN disclosed
CN-105330984-A TPV composition and automobile hand brake grip coating material ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2016-02-17 CN disclosed
CN-105330952-A TPV (thermoplastic vulcanizate) for heat-shrinkable casing pipe material of automobile wire harness ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2016-02-17 CN disclosed