SCHEMBL7064548

SCHEMBL7064548

NC(=O)c1ncc(Cl)c(Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
SIRT6 Q8N6T7 1/20 0.39
LMNA P02545 1/20 0.38
NNMT P40261 3/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ADORA3 P0DMS8 1/20 0.32
TSHR P16473 1/20 0.32
MC4R P32245 1/20 0.32
ADRA1A P35348 1/20 0.32
MC3R P41968 1/20 0.32
CDC7 O00311 1/20 0.32
ICAM1 P05362 1/20 0.32
SELE P16581 1/20 0.32
VCAM1 P19320 1/20 0.32
MAPK9 P45984 2/20 0.31
MAPK10 P53779 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2458526 0.81 MEN1 (0.42) LMNAMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL6637739 0.76 LRRK2 (0.40) POLBSIRT6LMNANNMTMEN1
SCHEMBL30405672 0.75 NOTUM (0.40) MEN1KMT2AALDH1A1
SCHEMBL28988545 0.75 NOTUM (0.40) MEN1KMT2AALDH1A1
SCHEMBL3172153 0.73 SIRT6 (0.45) POLBSIRT6LMNANNMTADORA3
SCHEMBL810771 0.70
SCHEMBL27462527 0.69 POLB (0.41) POLBSIRT6LMNAMEN1KMT2A
SCHEMBL29959449 0.69 ADORA3 (0.37) SIRT6NNMTKMT2AADORA3TSHR
SCHEMBL18760110 0.68 LMNA (0.32) SIRT6LMNA
SCHEMBL1684235 0.68 LCK (0.36) SIRT6LMNANNMTADORA3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030167575-A1 Method for coloring acrylic fibers CONNOLLY BRIAN ALAN (TW) 2003-09-11 US disclosed