Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064560 | 0.93 | HRH3 (0.39) | LMNAPPARDPPARATSHRKDM4E | |
| SCHEMBL7070089 | 0.83 | FFAR1 (0.36) | MAPTEPHX1LMNAKMT2AMEN1 | |
| SCHEMBL7065211 | 0.81 | IDO1 (0.39) | MAPTKMT2AMEN1PPARDPPARA | |
| SCHEMBL6497406 | 0.81 | BRD4 (0.41) | MAPTEPHX1LMNAKMT2AMEN1 | |
| SCHEMBL7068046 | 0.79 | HDAC1 (0.39) | LMNAKMT2AMEN1EPHX2PPARD | |
| SCHEMBL7068552 | 0.78 | KMT2A (0.43) | LMNAKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL6496310 | 0.78 | THRB (0.41) | KMT2AMEN1KDM4EP4HBNPSR1 | |
| SCHEMBL6301182 | 0.78 | KMT2A (0.47) | MAPTLMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL7132256 | 0.76 | KDM4E (0.35) | KDM4EP4HBNPSR1 | |
| SCHEMBL7132250 | 0.75 | KDM4E (0.35) | PPARAKDM4EP4HBNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |