Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068553 | 0.84 | MEN1 (0.45) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6489028 | 0.83 | L3MBTL1 (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6488038 | 0.82 | KMT2A (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6501155 | 0.81 | L3MBTL1 (0.42) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7064560 | 0.78 | HRH3 (0.39) | MAPK1L3MBTL1LMNA | |
| SCHEMBL7070085 | 0.78 | MAPT (0.36) | KMT2AMEN1CYP1A2SMN1; SMN2NPSR1 | |
| SCHEMBL7135143 | 0.77 | SMN1; SMN2 (0.48) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7065211 | 0.70 | IDO1 (0.39) | KMT2AMEN1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL10932416 | 0.67 | PPARA (0.44) | ALDH1A1 | |
| SCHEMBL7068046 | 0.66 | HDAC1 (0.39) | KMT2AMEN1NPSR1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |