Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.64 |
| ▸ | AGXT | P21549 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467207 | 0.82 | IDO1 (0.69) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| SCHEMBL3156367 | 0.79 | IDO1 (0.60) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| SCHEMBL6505160 | 0.79 | IDO1 (0.41) | IDO1AGXTMAPK14KDM5AKDM5B | |
| SCHEMBL706473 | 0.78 | IDO1 (0.64) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| SCHEMBL27613607 | 0.78 | IDO1 (0.64) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| SCHEMBL14042388 | 0.78 | IDO1 (1.00) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| SCHEMBL27593054 | 0.78 | IDO1 (0.64) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| Hydrochloric Acid SCHEMBL662142 | 0.77 | IDO1 (1.00) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| SCHEMBL12874169 | 0.75 | IDO1 (0.60) | IDO1AGXTKDM4ESMN1; SMN2MAOB | |
| SCHEMBL129245 | 0.75 | IDO1 (0.54) | IDO1AGXTKDM4ESMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2013-08-15 | — | — | US | claimed |
| US-20100234365-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2010-09-16 | — | — | US | claimed |
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |
| EP-1031575-B1 | Process for preparing growth hormone secretagogues | PFIZER PROD INC (US) | 2004-09-29 | — | — | EP | claimed |
| US-6686359-B2 | ANIMAL GROWTH REGULATORS; OSTEOPOROSIS; CONGESTIVE HEART FAILURE; MUSCULAR DISORDERS | PFIZER INC. | 2004-02-03 | — | — | US | claimed |
| US-6673929-B2 | Process for preparing growth hormone secretagogues | PFIZER INC. | 2004-01-06 | — | — | US | claimed |
| US-20030158414-A1 | Process for preparing growth hormone secretagogues | RAQUALIA PHARMA INC. (JP) | 2003-08-21 | — | — | US | claimed |
| US-20030130284-A1 | Growth hormone secretagogues | CARPINO PHILIP A (US) | 2003-07-10 | — | — | US | claimed |
| US-6559150-B2 | Neurotransmitter stimulants; antidiabetic agents; congestive heart failure; obesity; frailty; maintaining renal and catabolic homeostasis; bone fracture repair; reducing cachexia and protein loss; muscle strength and burns. | PFIZER INC. | 2003-05-06 | — | — | US | claimed |
| US-20020045622-A1 | Growth hormone secretagogues | CARPINO PHILIP A (US) | 2002-04-18 | — | — | US | claimed |
| US-20020002283-A1 | Process for preparing growth hormone secretagogues | RAQUALIA PHARMA INC. (JP) | 2002-01-03 | — | — | US | claimed |
| EP-1031575-A1 | Process for preparing growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-08-30 | — | — | EP | claimed |
| EP-0995748-A1 | Growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-04-26 | — | — | EP | claimed |
| EP-2280970-B1 | IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2014-01-08 | — | — | EP | disclosed |
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2013-08-15 | — | — | US | disclosed |
| US-8431607-B2 | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2013-04-30 | — | — | US | disclosed |
| US-20020002283-A1 | Process for preparing growth hormone secretagogues | RAQUALIA PHARMA INC. (JP) | 2002-01-03 | — | — | US | disclosed |
| EP-1031575-A1 | Process for preparing growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0995748-A1 | Growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002283-A1 | Process for preparing growth hormone secretagogues | GHRHR, GHSR, PRLHR | IDO1 3078/4885AGXT 587/4885KDM4E 3310/4885 |
| US-20020045622-A1 | Growth hormone secretagogues | GHSR, GHRHR, GIPR | IDO1 3206/4885AGXT 3392/4885KDM4E 4630/4885 |
| US-20030158414-A1 | Process for preparing growth hormone secretagogues | GHRHR, GHSR, PRLHR | IDO1 3078/4885AGXT 587/4885KDM4E 3310/4885 |
| US-20030130284-A1 | Growth hormone secretagogues | GHSR, GHRHR, GIPR | IDO1 3206/4885AGXT 3392/4885KDM4E 4630/4885 |
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | CNR1, CNR2, FAAH | IDO1 1280/4885AGXT 4097/4885KDM4E 1763/4885 |
| US-20100234365-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | CNR1, CNR2, FAAH | IDO1 1280/4885AGXT 4097/4885KDM4E 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.