Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.64 |
| ▸ | AGXT | P21549 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.39 |
| ▸ | MYLK | Q15746 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22519888 | 0.83 | IDO1 (0.55) | IDO1AGXTMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL12016019 | 0.83 | IDO1 (0.44) | IDO1AGXTALDH1A1MAPTMEN1 | |
| SCHEMBL29467207 | 0.82 | IDO1 (0.69) | IDO1AGXTMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL12200028 | 0.81 | IDO1 (0.53) | IDO1AGXTMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL15132099 | 0.81 | IDO1 (0.53) | IDO1AGXTMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL12887573 | 0.81 | MMP1 (0.43) | IDO1AGXTMAOBTDP1 | |
| SCHEMBL12121014 | 0.81 | IDO1 (0.42) | IDO1AGXTMAOBKDM4EALDH1A1 | |
| SCHEMBL19321459 | 0.80 | MEN1 (0.49) | IDO1AGXTMAOBKDM4EALDH1A1 | |
| SCHEMBL17071869 | 0.79 | L3MBTL1 (0.47) | IDO1AGXTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6505166 | 0.79 | IDO1 (0.41) | IDO1AGXTMEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2013-08-15 | — | — | US | claimed |
| US-20100234365-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2010-09-16 | — | — | US | claimed |
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |
| EP-1031575-B1 | Process for preparing growth hormone secretagogues | PFIZER PROD INC (US) | 2004-09-29 | — | — | EP | claimed |
| US-6686359-B2 | ANIMAL GROWTH REGULATORS; OSTEOPOROSIS; CONGESTIVE HEART FAILURE; MUSCULAR DISORDERS | PFIZER INC. | 2004-02-03 | — | — | US | claimed |
| US-6673929-B2 | Process for preparing growth hormone secretagogues | PFIZER INC. | 2004-01-06 | — | — | US | claimed |
| US-20030158414-A1 | Process for preparing growth hormone secretagogues | RAQUALIA PHARMA INC. (JP) | 2003-08-21 | — | — | US | claimed |
| US-20030130284-A1 | Growth hormone secretagogues | CARPINO PHILIP A (US) | 2003-07-10 | — | — | US | claimed |
| US-6559150-B2 | Neurotransmitter stimulants; antidiabetic agents; congestive heart failure; obesity; frailty; maintaining renal and catabolic homeostasis; bone fracture repair; reducing cachexia and protein loss; muscle strength and burns. | PFIZER INC. | 2003-05-06 | — | — | US | claimed |
| US-20020045622-A1 | Growth hormone secretagogues | CARPINO PHILIP A (US) | 2002-04-18 | — | — | US | claimed |
| US-20020002283-A1 | Process for preparing growth hormone secretagogues | RAQUALIA PHARMA INC. (JP) | 2002-01-03 | — | — | US | claimed |
| EP-1031575-A1 | Process for preparing growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-08-30 | — | — | EP | claimed |
| EP-0995748-A1 | Growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-04-26 | — | — | EP | claimed |
| EP-4230620-A1 | SUBSTITUTED N-AMINO-N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | Bayer Aktiengesellschaft (DE) | 2023-08-23 | — | — | EP | disclosed |
| EP-4230621-A1 | SUBSTITUTED N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | Bayer AG (DE) | 2023-08-23 | — | — | EP | disclosed |
| WO-2023107563-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20020002283-A1 | Process for preparing growth hormone secretagogues | RAQUALIA PHARMA INC. (JP) | 2002-01-03 | — | — | US | disclosed |
| EP-1031575-A1 | Process for preparing growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0995748-A1 | Growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002283-A1 | Process for preparing growth hormone secretagogues | GHRHR, GHSR, PRLHR | IDO1 3078/4885AGXT 587/4885MAOB 2102/4885 |
| US-20020045622-A1 | Growth hormone secretagogues | GHSR, GHRHR, GIPR | IDO1 3206/4885AGXT 3392/4885MAOB 4003/4885 |
| US-20030158414-A1 | Process for preparing growth hormone secretagogues | GHRHR, GHSR, PRLHR | IDO1 3078/4885AGXT 587/4885MAOB 2102/4885 |
| US-20030130284-A1 | Growth hormone secretagogues | GHSR, GHRHR, GIPR | IDO1 3206/4885AGXT 3392/4885MAOB 4003/4885 |
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | CNR1, CNR2, FAAH | IDO1 1280/4885AGXT 4097/4885MAOB 1474/4885 |
| US-20100234365-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | CNR1, CNR2, FAAH | IDO1 1280/4885AGXT 4097/4885MAOB 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.