Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913722 | 0.81 | RAB9A (0.50) | RAB9ANPC1KMT2AL3MBTL1ATM | |
| SCHEMBL7064969 | 0.79 | ITGB2 (0.49) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3721530 | 0.68 | KMT2A (0.54) | RAB9ANPC1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6217665 | 0.68 | ITGB2 (0.48) | RAB9ANPC1KMT2AL3MBTL1ATM | |
| SCHEMBL425351 | 0.67 | SMN1; SMN2 (0.57) | RAB9ANPC1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11479783 | 0.66 | KMT2A (0.67) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5830370 | 0.66 | ITGB2 (0.54) | RAB9ANPC1KMT2AATMALDH1A1 | |
| SCHEMBL7662359 | 0.66 | L3MBTL1 (0.50) | RAB9ANPC1KMT2AL3MBTL1ATM | |
| SCHEMBL3033526 | 0.66 | SMN1; SMN2 (0.66) | KMT2AL3MBTL1SMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL7064158 | 0.66 | KDM4E (0.36) | KMT2AMEN1CYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |