Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713785 | 0.81 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BOPRM1DRD2 | |
| SCHEMBL6770595 | 0.81 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BOPRM1 | |
| Hydrochloric Acid SCHEMBL6642002 | 0.81 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL6645059 | 0.68 | ADRA1A (0.66) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6718413 | 0.67 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL6767632 | 0.67 | ADRA1D (0.67) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6713792 | 0.63 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BOPRM1DRD2 | |
| Hydrochloric Acid SCHEMBL6646907 | 0.63 | ADRA1A (0.55) | ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL7521827 | 0.60 | OPRM1 (0.58) | OPRM1SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL6688186 | 0.59 | OPRM1 (0.43) | ADRA1DADRA1AADRA1BOPRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | ADRA1D 247/4885ADRA1A 224/4885ADRA1B 306/4885 |
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | ADRA1D 247/4885ADRA1A 224/4885ADRA1B 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.