Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 18/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.35 |
| ▸ | ITGAL | P20701 | 18/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065998 | 0.81 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL7063009 | 0.81 | ITGB2 (0.41) | ITGB2ICAM1ITGAL | |
| SCHEMBL7645298 | 0.78 | ITGB2 (0.52) | ITGB2ICAM1ITGAL | |
| SCHEMBL6817901 | 0.78 | ITGB2 (0.52) | ITGB2ICAM1ITGAL | |
| SCHEMBL7064160 | 0.78 | F2R (0.38) | ITGB2ICAM1ITGALGPR183 | |
| SCHEMBL6919430 | 0.76 | RAB9A (0.39) | ITGB2ICAM1ITGAL | |
| SCHEMBL7065196 | 0.74 | NPC1 (0.32) | — | |
| SCHEMBL7065799 | 0.73 | GPR183 (0.36) | ITGB2ICAM1ITGALGPR183 | |
| SCHEMBL6813244 | 0.73 | HRH3 (0.38) | ITGB2ICAM1ITGAL | |
| SCHEMBL6919311 | 0.67 | ITGAL (0.51) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |