Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227767 | 0.75 | HDAC1 (0.50) | TDP1HDAC1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL1708819 | 0.72 | HDAC1 (0.62) | TDP1HDAC1HDAC3HDAC2MEN1 | |
| SCHEMBL8110762 | 0.72 | HDAC2 (0.83) | HDAC1HDAC3HDAC2MAPTKDM4E | |
| SCHEMBL11642610 | 0.72 | MTNR1A (0.58) | HDAC1HDAC3HDAC2MEN1KMT2A | |
| SCHEMBL24405269 | 0.71 | HDAC1 (0.57) | HDAC1HDAC3HDAC2MEN1KMT2A | |
| SCHEMBL10372226 | 0.71 | HDAC1 (0.60) | HDAC1HDAC3HDAC2MAPTALDH1A1 | |
| SCHEMBL11512570 | 0.71 | HDAC1 (0.60) | HDAC1HDAC3HDAC2MEN1KMT2A | |
| SCHEMBL11207191 | 0.71 | HDAC1 (0.60) | TDP1HDAC1HDAC3HDAC2KMT2A | |
| SCHEMBL30832967 | 0.71 | HDAC1 (0.60) | TDP1HDAC1HDAC3HDAC2KMT2A | |
| SCHEMBL22476617 | 0.70 | HTT (0.49) | TDP1HDAC1HDAC3HDAC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579326-B2 | For dyeing hair | L'OREAL S.A. (FR) | 2003-06-17 | — | — | US | disclosed |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | BRETON PHILIPPE (FR) | 2001-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | KRT18, INMT, KMO | TDP1 2965/4885HDAC1 571/4885HDAC3 687/4885 |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | KRT18, INMT, KMO | TDP1 3046/4885HDAC1 466/4885HDAC3 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.