Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.44 |
| ▸ | RELA | Q04206 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065056 | 0.86 | RAB9A (0.39) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL8553142 | 0.84 | RAB9A (0.55) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL7061221 | 0.79 | CYP3A4 (0.39) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL8552022 | 0.74 | RARB (0.41) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL7061245 | 0.74 | RARB (0.41) | RAB9ANPC1TP53HPGDRARB | |
| SCHEMBL7062989 | 0.73 | CYP3A4 (0.37) | CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7064930 | 0.73 | S1PR1 (0.39) | ALDH1A1HPGDS1PR3 | |
| SCHEMBL9159826 | 0.73 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9153631 | 0.73 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9158294 | 0.73 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027403-B1 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-28 | — | — | EP | disclosed |
| US-6485797-B1 | 5-Arylindane derivatives and ferroelectric liquid crystal mixture containing same | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-11-26 | — | — | US | disclosed |
| EP-1027403-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999019420-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-22 | — | — | WO | disclosed |