Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 8/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651093 | 0.91 | CTRB1 (0.48) | CTRB1SYKCASP1CTSLCTSS | |
| SCHEMBL6652290 | 0.86 | HTT (0.63) | CTRB1CASP1HTT | |
| SCHEMBL17816593 | 0.86 | CTSL (0.55) | CTRB1SYKCTSLCTSS | |
| SCHEMBL6649610 | 0.86 | HTT (0.63) | CTRB1CASP1HTT | |
| SCHEMBL6649364 | 0.86 | CASP1 (0.52) | CTRB1CASP1HTTITGB3ITGA2B | |
| SCHEMBL6650048 | 0.86 | HTT (0.55) | CTRB1SYKCASP1CTSLCTSS | |
| SCHEMBL8367591 | 0.85 | SIRT2 (0.55) | CTRB1CTSLCTSS | |
| SCHEMBL6649361 | 0.84 | CTRB1 (0.48) | CTRB1SYKCASP1CTSLCTSS | |
| SCHEMBL9574175 | 0.84 | CASP1 (0.60) | CTRB1SYKCASP1HTTITGB3 | |
| SCHEMBL1024311 | 0.83 | FOLH1 (0.61) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617332-B1 | Cyclic amidinourea derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-09 | — | — | US | disclosed |