Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819092 | 0.78 | SLC1A3 (0.43) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL2269233 | 0.71 | SLC1A3 (0.49) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL7821068 | 0.71 | SLC1A1 (0.43) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL7821232 | 0.66 | CYP1A2 (0.39) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7808946 | 0.66 | CYP1A2 (0.39) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7419397 | 0.66 | CASP1 (0.48) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL4829905 | 0.66 | SLC1A3 (0.40) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL9254953 | 0.65 | SLC1A2 (0.61) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL13173217 | 0.65 | SLC1A2 (0.61) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 | |
| SCHEMBL10126136 | 0.65 | SLC1A2 (0.61) | SLC1A2SLC1A1MEN1KMT2ASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617332-B1 | Cyclic amidinourea derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-09 | — | — | US | disclosed |