SCHEMBL7808946

SCHEMBL7808946

CC(C)(C)OC(Cc1ccccc1)[C@H](N=C=O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTPN7 P35236 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SRR Q9GZT4 2/20 0.38
CTSS P25774 2/20 0.38
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
CTSK P43235 1/20 0.38
ALPI P09923 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7821232 1.00 CYP1A2 (0.39) CYP1A2KDM4EMEN1POLBMAPT
SCHEMBL7819092 0.81 SLC1A3 (0.43) CYP1A2KDM4EMEN1POLBMAPT
SCHEMBL5788697 0.79 CTSS (0.34) CYP1A2SRRCTSSCTSLCTSB
SCHEMBL7955439 0.78 CTSS (0.31) CTSSCTSK
SCHEMBL8932578 0.77 CTSS (0.42) SRRCTSSCTSKACEPPARG
SCHEMBL11094947 0.75 SLC1A3 (0.53) CYP1A2KDM4EMEN1POLBMAPT
SCHEMBL27857348 0.75 SLC1A3 (0.53) CYP1A2KDM4EMEN1POLBMAPT
SCHEMBL5792810 0.74 SRR (0.39) SRRCTSSCTSLCTSBCTSK
SCHEMBL12483826 0.72 ITGA4 (0.48) POLBMAPTTDP1CTSSCTSL
SCHEMBL10441236 0.72 ITGA4 (0.48) POLBMAPTTDP1CTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1078919-A1 SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME KANEKA CORPORATION (JP) 2001-02-28 EP disclosed