SCHEMBL7065616

SCHEMBL7065616

CC(C)(CO)COP(=O)(O)Cl

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.40
GRM4 Q14833 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PPARD Q03181 1/20 0.30
NUDT1 P36639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25071173 0.83 GRM4 (0.31) GRM4TP53TDP1
SCHEMBL628929 0.82 DGAT1 (0.42) DGAT1GRM4
SCHEMBL2782188 0.81 TP53 (0.36) GRM4TP53TDP1PPARD
SCHEMBL28315800 0.81 LMNA (0.36) GRM4
SCHEMBL24931641 0.81 GRM4 (0.30) GRM4TP53TDP1
SCHEMBL518185 0.80 DGAT1 (0.41) DGAT1GRM4PPARD
SCHEMBL25071540 0.79 FDPS (0.42) GRM4TP53TDP1
SCHEMBL11126648 0.77 ALDH1A1 (0.30) TP53
SCHEMBL7128559 0.77 DGAT1 (0.42) DGAT1GRM4PPARD
SCHEMBL3620192 0.77 DGAT1 (0.39) DGAT1GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617379-B2 N,N'-piperazinebis(neopentylglycol)phosphoramidate in combination with at least one co-additive which is either melamine or a melamine derivative such as melamine cyanurate or melamine pyrophosphate ALBEMARLE CORPORATION 2003-09-09 US disclosed
WO-2003048247-A1 FLAME RETARDANT POLYMER COMPOSITIONS ALBEMARLE CORPORATION (US) 2003-06-12 WO disclosed
US-20030109608-A1 Flame retardant polymer compositions ALBEMARLE CORPORATION 2003-06-12 US disclosed