Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043424 | 0.74 | QDPR (0.57) | HTR2CSIGMAR1NISCH | |
| SCHEMBL21087138 | 0.72 | HTR2C (0.47) | HTR2CSIGMAR1HTR2B | |
| SCHEMBL2929152 | 0.71 | CALM1 (0.46) | FYNSIGMAR1CALM1PTGS2GABRA1 | |
| SCHEMBL18015825 | 0.71 | MAPT (0.55) | CHRM3FYNCALM1PTGS2GABRA1 | |
| SCHEMBL16675752 | 0.71 | FYN (0.59) | FYNCALM1PTGS2GABRA1GABRB2 | |
| SCHEMBL7404347 | 0.70 | SIGMAR1 (0.50) | CHRM3CHRM1HTR2CSIGMAR1HTR2A | |
| SCHEMBL2692579 | 0.70 | CA12 (0.59) | PTGS2GABRA1GABRB2 | |
| SCHEMBL29629010 | 0.70 | PTGS2 (0.58) | PTGS2GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL1574641 | 0.69 | HTR2C (0.52) | CHRM3CHRM1HTR2CSIGMAR1HTR2A | |
| SCHEMBL11204336 | 0.68 | SIGMAR1 (0.67) | HTR2CSIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058727-A1 | SUBSTITUTED 3,5-DIHYDRO-4H-IMIDAZOL-4-ONES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |