SCHEMBL7065725

SCHEMBL7065725

Cc1ccc(S(=O)(=O)OCCC(OS(=O)(=O)c2ccc(C)cc2)C(=O)OCCc2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
LMNA P02545 1/20 0.40
FKBP1A P62942 2/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
CNR2 P34972 1/20 0.38
STAT3 P40763 1/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7971248 0.93 FKBP1A (0.41) ALDH1A1CA1CA2LMNAFKBP1A
SCHEMBL7973259 0.92 FKBP1A (0.43) ALDH1A1CA1CA2LMNAFKBP1A
SCHEMBL7067287 0.92 CA1 (0.40) ALDH1A1CA1CA2LMNAFKBP1A
SCHEMBL7064562 0.90 LMNA (0.49) ALDH1A1CA1CA2LMNAMAPT
SCHEMBL7973451 0.85 CA1 (0.38) ALDH1A1CA1CA2LMNAFKBP1A
SCHEMBL7064469 0.84 KMT2A (0.42) ALDH1A1CA1CA2LMNAGAA
SCHEMBL7971433 0.84 FKBP1A (0.38) ALDH1A1CA1CA2LMNAFKBP1A
SCHEMBL7060903 0.84 HTT (0.39) ALDH1A1LMNAGAASTAT3KMT2A
SCHEMBL7975992 0.83 LMNA (0.47) CA1CA2LMNAFKBP1AMAPT
SCHEMBL7067264 0.82 PLA2G2C (0.39) ALDH1A1CA1CA2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed