Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973451 | 0.96 | CA1 (0.38) | FKBP1ACA1CA2CA9HCAR2 | |
| SCHEMBL7973259 | 0.92 | FKBP1A (0.43) | FKBP1ACA1CA2PPARGPTGES | |
| SCHEMBL7067287 | 0.91 | CA1 (0.40) | FKBP1ACA1CA2CA9HCAR2 | |
| SCHEMBL7976230 | 0.89 | CTRC (0.38) | CA1CA2CA9LMNATDP1 | |
| SCHEMBL7971248 | 0.89 | FKBP1A (0.41) | FKBP1ACA1CA2PPARGPTGES | |
| SCHEMBL7971318 | 0.86 | CTRC (0.40) | LMNANPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL7969622 | 0.85 | TDP1 (0.42) | NPC1RAB9ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7969990 | 0.85 | ALDH1A1 (0.38) | CA1CA2CA9LMNATDP1 | |
| SCHEMBL7969965 | 0.85 | TSHR (0.43) | PPARGLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL7972944 | 0.84 | KMT2A (0.39) | CA2CA9NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |