Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976225 | 0.93 | TDP1 (0.39) | HTTSMN1; SMN2ALDH1A1STAT3PTGES | |
| SCHEMBL7976100 | 0.92 | CYP24A1 (0.37) | HTTSMN1; SMN2ALDH1A1STAT3PTGES | |
| SCHEMBL7065836 | 0.91 | MAPT (0.41) | SMN1; SMN2PTGES | |
| SCHEMBL7064562 | 0.85 | LMNA (0.49) | ALDH1A1LMNA | |
| SCHEMBL7973159 | 0.84 | MAPT (0.39) | SMN1; SMN2PTGES | |
| SCHEMBL7065725 | 0.84 | ALDH1A1 (0.42) | ALDH1A1STAT3KMT2AGAALMNA | |
| SCHEMBL7064469 | 0.84 | KMT2A (0.42) | SMN1; SMN2ALDH1A1STAT3KMT2AGAA | |
| SCHEMBL7066596 | 0.84 | STAT3 (0.42) | HTTSMN1; SMN2ALDH1A1STAT3KMT2A | |
| SCHEMBL7959874 | 0.83 | MAPT (0.39) | SMN1; SMN2PTGES | |
| SCHEMBL7065786 | 0.83 | STAT3 (0.37) | ALDH1A1STAT3KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |