SCHEMBL7065737

SCHEMBL7065737

CC(=O)Nc1ccc2cc(S(=O)(=O)O)[c]c(O)c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.45
NT5E P21589 1/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
MAPT P10636 4/20 0.43
KDM4E B2RXH2 3/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
GLA P06280 1/20 0.43
TNNI3 P19429 1/20 0.43
TNNT2 P45379 1/20 0.43
TNNC1 P63316 1/20 0.43
RUNX1 Q01196 1/20 0.43
CBFB Q13951 1/20 0.43
CA2 P00918 2/20 0.41
ALDH1A1 P00352 4/20 0.40
PRMT3 O60678 1/20 0.40
EP300 Q09472 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT1 Q99873 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7063764 0.89 PRMT1 (0.47) ENPP2NT5EKMT2AMEN1MAPT
SCHEMBL7893223 0.82 ING2 (0.47) ENPP2KMT2AMEN1MAPTNPC1
SCHEMBL7068270 0.80 CA2 (0.48) ENPP2KMT2AMEN1MAPTKDM4E
SCHEMBL8636006 0.77 ABL1 (0.39) NT5ECA2ALDH1A1CASP6CA1
SCHEMBL4653442 0.76 MEN1 (0.46) ENPP2KMT2AMEN1MAPTKDM4E
SCHEMBL9439943 0.76 ENPP2 (0.51) ENPP2NT5EKMT2AMEN1MAPT
SCHEMBL9770987 0.76 LMNA (0.50) ENPP2KMT2AMEN1MAPTCA2
SCHEMBL6635390 0.75 HSD17B10 (0.50) NT5EKMT2AMEN1MAPTKDM4E
SCHEMBL1803095 0.75 NT5E (0.56) ENPP2NT5EKMT2AMEN1MAPT
SCHEMBL1803097 0.75 NT5E (0.75) ENPP2NT5EKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765965-B1 Process for deying synthetic fibrous polyamid materials DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-06-04 EP disclosed
US-6177552-B1 CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-23 US disclosed
EP-0765918-B1 Reactive dye preparations DYSTAR TEXTILFARBEN GMBH & CO (DE) 1999-07-28 EP disclosed
US-5810890-A USING SPECIFIED MIXTURE OF DYES; INCREASED BRIGHTNESS AND LEVELNESS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-09-22 US disclosed
US-5803930-A MIXTURE OF TWO DIFFERENT WATER SOLUBLE DYES; DYEING SYNTHETIC POLYAMIDES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-09-08 US disclosed
EP-0765918-A2 Reactive dye preparations DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed
EP-0765965-A2 Process for deying synthetic fibrous polyamid materials DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed