SCHEMBL7063764

SCHEMBL7063764

CC(=O)Nc1ccc2c(O)[c]c(S(=O)(=O)O)cc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.47
PRMT3 O60678 1/20 0.45
EP300 Q09472 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
CASP6 P55212 2/20 0.42
ENPP2 Q13822 1/20 0.42
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
GLA P06280 1/20 0.40
TNNI3 P19429 1/20 0.40
TNNT2 P45379 1/20 0.40
RAB9A P51151 1/20 0.40
TNNC1 P63316 1/20 0.40
RUNX1 Q01196 1/20 0.40
CBFB Q13951 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7065737 0.89 ENPP2 (0.45) PRMT1PRMT3EP300PRMT6CASP6
SCHEMBL7068246 0.82 CASP6 (0.50) PRMT1CASP6MEN1MAPTKMT2A
SCHEMBL2210354 0.78 CASP6 (0.47) PRMT1CASP6ALDH1A1MEN1KMT2A
SCHEMBL7068270 0.77 CA2 (0.48) PRMT1PRMT3EP300PRMT6CASP6
SCHEMBL3481043 0.76 PRMT1 (0.78) PRMT1PRMT3EP300PRMT6CASP6
SCHEMBL9770987 0.76 LMNA (0.50) ENPP2ALDH1A1MEN1MAPTKMT2A
SCHEMBL4117391 0.75 PRMT1 (0.76) PRMT1PRMT3EP300PRMT6CASP6
SCHEMBL8608288 0.74 CTDSP1 (0.47) PRMT1CASP6ENPP2ALDH1A1MEN1
SCHEMBL2152539 0.74 CASP6 (0.54) PRMT1CASP6ENPP2ALDH1A1MAPT
SCHEMBL11438339 0.73 PRMT1 (0.56) PRMT1PRMT3EP300PRMT6CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0343262-B1 FIBRE-REACTIVE AZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR DYEING HYDROXY- AND/OR CARBOXAMIDE GROUPS CONTAINING FIBRE-MATERIAL HOECHST CELANESE CORPORATION (US) 1993-03-17 EP claimed
EP-0343262-A1 Fibre-reactive azo dyes, process for their preparation and their use for dyeing hydroxy- and/or carboxamide groups containing fibre-material HOECHST CELANESE CORPORATION (US) 1989-11-29 EP claimed
EP-0765965-B1 Process for deying synthetic fibrous polyamid materials DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-06-04 EP disclosed
US-6177552-B1 CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-23 US disclosed
EP-0765918-B1 Reactive dye preparations DYSTAR TEXTILFARBEN GMBH & CO (DE) 1999-07-28 EP disclosed
US-5810890-A USING SPECIFIED MIXTURE OF DYES; INCREASED BRIGHTNESS AND LEVELNESS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-09-22 US disclosed
US-5803930-A MIXTURE OF TWO DIFFERENT WATER SOLUBLE DYES; DYEING SYNTHETIC POLYAMIDES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-09-08 US disclosed
EP-0765965-A2 Process for deying synthetic fibrous polyamid materials DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed
EP-0765918-A2 Reactive dye preparations DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed
US-5373094-A Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine group ZENECA LIMITED (GB) 1994-12-13 US disclosed
EP-0576143-A2 Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group ZENECA LIMITED (GB) 1993-12-29 EP disclosed