Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893136 | 0.84 | CHRNA7 (0.51) | POLBLMNAMAPTMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6437878 | 0.72 | KMT2A (0.44) | POLBLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL5610349 | 0.70 | NOTUM (0.46) | LMNAHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL689377 | 0.70 | MAPT (0.46) | ABCB1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6364038 | 0.69 | PTGES (0.49) | ABCB1CHEK1MAPTMEN1ALDH1A1 | |
| SCHEMBL7294542 | 0.69 | MAPT (0.66) | POLBCHEK1LMNAHTTMAPT | |
| SCHEMBL4857109 | 0.68 | CHEK1 (0.76) | CHEK1 | |
| SCHEMBL13097411 | 0.68 | GRM5 (0.56) | LMNAHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL5569349 | 0.67 | SMN1; SMN2 (0.55) | LMNAHTTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2063456 | 0.67 | MAPT (0.67) | LMNAHTTMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037784-A2 | PYRROLIDONES WITH ANTI-HIV ACTIVITY | IRM LLC (BM) | 2004-05-06 | — | — | WO | disclosed |