Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281281 | 0.95 | KDM4E (0.51) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| SCHEMBL29180667 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| SCHEMBL3264151 | 0.86 | DGAT1 (0.39) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| SCHEMBL13727788 | 0.84 | MEN1 (0.39) | MEN1MAPTKMT2ALMNACYP3A4 | |
| SCHEMBL9952304 | 0.81 | KDM4E (0.49) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| SCHEMBL3947074 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| SCHEMBL27788443 | 0.78 | HCRTR1 (0.49) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL27788449 | 0.77 | HCRTR1 (0.48) | ALDH1A1KDM4ENFKB1MEN1MAPT | |
| SCHEMBL83673 | 0.76 | PTGS2 (0.40) | ALDH1A1KDM4EMAPTLMNACYP3A4 | |
| SCHEMBL18036607 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111011-A2 | SYNTHESIS OF 2-ARYL PYRIMIDINE 4-CARBOXYLIC ACID AMIDES | EURO-CELTIQUE S.A. (LU) | 2004-12-23 | — | — | WO | disclosed |