Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774956 | 0.92 | CRHR1 (0.39) | CRHR1ALOX15ALOX12 | |
| SCHEMBL6774429 | 0.75 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL6777461 | 0.73 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6775942 | 0.73 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL6774526 | 0.73 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6775364 | 0.71 | ALOX15 (0.35) | ALOX15ALOX12 | |
| SCHEMBL6889787 | 0.67 | CRHR1 (0.42) | CRHR1ALOX15 | |
| SCHEMBL6773897 | 0.66 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL6781376 | 0.66 | MEN1 (0.39) | CRHR1ALOX15 | |
| SCHEMBL6780509 | 0.66 | MEN1 (0.39) | CRHR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191125-A1 | Aryloxy- and arylthiosubstituted pyrimidines and triazines and derivatives thereof | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-10-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191125-A1 | Aryloxy- and arylthiosubstituted pyrimidines and triazines and derivatives thereof | PARL, HTR5A, PSEN2 | CRHR1 51/4885ALOX15 439/4885ALOX12 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.