Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066409 | 0.84 | GRIN2D (0.44) | MAOBHCAR2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL692402 | 0.80 | KMT2A (0.55) | MAOBHCAR2RAB9AMAPTMAOA | |
| SCHEMBL9921935 | 0.77 | CA12 (0.53) | MAOBRAB9AMAPTMAOAKDM4E | |
| SCHEMBL6193636 | 0.76 | SRD5A2 (0.54) | MAOBRAB9AMAPTSRD5A2ALDH1A1 | |
| SCHEMBL30196606 | 0.75 | ALDH1A1 (0.63) | HCAR2RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL691707 | 0.75 | ALDH1A1 (0.63) | HCAR2RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL26255857 | 0.74 | TDP1 (0.57) | RAB9AMAPTKDM4EALDH1A1KMT2A | |
| P-Xylene SCHEMBL7126322 | 0.74 | MAPT (0.49) | RAB9AMAPTKDM4ESRD5A2ALDH1A1 | |
| SCHEMBL9762060 | 0.73 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2BGRIN2CRAB9A | |
| SCHEMBL6001946 | 0.73 | KMT2A (0.64) | RAB9AMAPTKDM4EMRGPRX4SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030077768-A1 | Use of xylene monooxygenase for the oxidation of substituted polycyclic aromatic compounds | E.I. DU PONT DE NEMOURS AND COMPANY | 2003-04-24 | — | — | US | disclosed |