SCHEMBL692402

SCHEMBL692402

O=Cc1ccc2cc(C(=O)OCc3ccccc3)ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.55
TDP1 Q9NUW8 4/20 0.55
SLC6A2 P23975 1/20 0.55
SLC6A3 Q01959 1/20 0.55
LMNA P02545 3/20 0.55
RAB9A P51151 5/20 0.52
MAPT P10636 4/20 0.52
ALDH1A1 P00352 4/20 0.52
NPC1 O15118 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HPGD P15428 1/20 0.49
KDM4E B2RXH2 2/20 0.48
HTT P42858 1/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6002245 0.88 KMT2A (0.70) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL2706461 0.85 KMT2A (0.66) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL380997 0.85 KMT2A (0.71) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL313874 0.84 TDP1 (0.65) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL6001946 0.84 KMT2A (0.64) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL9616998 0.82 LMNA (0.71) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL7066405 0.80 MAOB (0.40) KMT2ARAB9AMAPTALDH1A1KDM4E
SCHEMBL6000300 0.80 KMT2A (0.58) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL3235219 0.80 ALOX5 (0.61) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL6001726 0.80 KMT2A (0.58) KMT2ATDP1SLC6A2SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 678 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2024-07-23 US disclosed
EP-4384508-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-06-19 EP disclosed
WO-2024031051-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-02-08 WO disclosed
WO-2024006937-A1 LIPID COMPOSITIONS FOR IN VIVO DELIVERY Life Technologies Corporation (US) 2024-01-04 WO disclosed
US-20240000966-A1 Lipid Compositions For In Vivo Delivery Life Technologies Corporation 2024-01-04 US disclosed
US-11850237-B2 Compounds and methods for treating influenza ROMARK LABORATORIES L.C. (US) 2023-12-26 US disclosed
WO-2023018990-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2023-02-16 WO disclosed
EP-2445349-B1 COMPOUNDS AND METHODS FOR TREATING INFLUENZA ROMARK LABORATORIES LC (US) 2022-02-09 EP disclosed
US-20210323984-A1 POL YCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. 2021-10-21 US disclosed
EP-3895706-A1 THIAZOLINIDE COMPOUNDS FOR TREATING NON-INFLUENZA VIRAL INFECTIONS Romark Laboratories, L.C. (US) 2021-10-20 EP disclosed
EP-0558630-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1993-09-08 EP disclosed
EP-0554400-A1 RETROVIRAL PROTEASE INHIBITORS. MONSANTO CO (US) 1993-08-11 EP disclosed
US-5157041-A Viricides HOFFMANN-LA ROCHE INC. (US) 1992-10-20 US disclosed
WO-1992008700-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008701-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008698-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008699-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008688-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
EP-0432694-A2 Aminoalcohols F. HOFFMANN-LA ROCHE AG (CH) 1991-06-19 EP disclosed
EP-0346847-A2 Amino acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP KMT2A 489/4885TDP1 1152/4885SLC6A2 2803/4885
US-20240000966-A1 Lipid Compositions For In Vivo Delivery CHMP4B, LIPA, CETP KMT2A 3841/4885TDP1 2476/4885SLC6A2 2935/4885
US-11850237-B2 Compounds and methods for treating influenza HIF1AN, HAVCR2, NEU1 KMT2A 2029/4885TDP1 4414/4885SLC6A2 2749/4885
US-20210323984-A1 POL YCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS POLRMT, PHOSPHO1, MBOAT7 KMT2A 943/4885TDP1 287/4885SLC6A2 3017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.