Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848524 | 0.86 | DRD2 (0.51) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL17844990 | 0.81 | ADRA1D (0.47) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL3436759 | 0.77 | TRPV1 (0.49) | DRD2DRD4DRD3TRPV1KMT2A | |
| SCHEMBL25400394 | 0.74 | KDM4E (0.55) | ADRA1DADRA1AADRA1BRAB9A | |
| SCHEMBL19032346 | 0.72 | TRPV1 (0.67) | DRD2DRD4DRD3TRPV1KMT2A | |
| SCHEMBL2472086 | 0.71 | ATM (0.43) | OPRL1 | |
| SCHEMBL30417089 | 0.71 | TRPV1 (0.51) | DRD2DRD4DRD3TRPV1OPRL1 | |
| SCHEMBL7067307 | 0.71 | DRD2 (0.60) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL8300352 | 0.70 | ATM (0.43) | SMYD2OPRL1 | |
| SCHEMBL2614922 | 0.70 | OPRL1 (0.59) | DRD2DRD4DRD3TRPV1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | DRD2 271/4885DRD4 179/4885DRD3 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.