Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848950 | 0.84 | DRD2 (0.55) | DRD2SLC6A4KDM4EHSD17B10HRH3 | |
| SCHEMBL7957071 | 0.83 | DRD2 (0.54) | DRD2SLC6A4KDM4EHSD17B10HRH3 | |
| SCHEMBL17844990 | 0.82 | ADRA1D (0.47) | DRD2SLC6A4KDM4EHSD17B10CCR2 | |
| SCHEMBL7957074 | 0.80 | DRD2 (0.58) | DRD2SLC6A4KDM4EHSD17B10HRH3 | |
| SCHEMBL9032338 | 0.78 | SLC6A4 (0.70) | DRD2SLC6A4HRH3ADRA1DHTR1D | |
| SCHEMBL3660571 | 0.78 | DRD2 (0.62) | DRD2SLC6A4KDM4EHRH3DRD4 | |
| SCHEMBL7960244 | 0.78 | DRD2 (0.62) | DRD2SLC6A4KDM4EHSD17B10HRH3 | |
| SCHEMBL1727824 | 0.78 | DRD3 (0.75) | DRD2SLC6A4DRD4HTR1AHTR2A | |
| SCHEMBL1593660 | 0.77 | NPY1R (0.63) | KDM4EHSD17B10CCR2ADRA1DADRA1A | |
| SCHEMBL6710735 | 0.77 | SLC6A4 (0.68) | DRD2SLC6A4HRH3ADRA1DHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | DRD2 271/4885SLC6A4 207/4885KDM4E 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.