SCHEMBL7066561

SCHEMBL7066561

N#Cc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.62
USP2 O75604 1/20 0.62
GAA P10253 1/20 0.62
KMT2A Q03164 1/20 0.62
KEAP1 Q14145 1/20 0.62
NFE2L2 Q16236 1/20 0.62
HPGD P15428 3/20 0.54
LMNA P02545 2/20 0.54
ALDH1A1 P00352 1/20 0.54
CYP1A2 P05177 1/20 0.54
PGR P06401 1/20 0.54
CYP2D6 P10635 1/20 0.54
SLC6A2 P23975 1/20 0.54
PDE4A P27815 1/20 0.54
MAPK1 P28482 1/20 0.54
CYP2C19 P33261 1/20 0.54
HRH1 P35367 1/20 0.54
HTT P42858 1/20 0.54
SLC6A3 Q01959 1/20 0.54
PDE4D Q08499 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7328069 0.87 HNF4A (0.50) MEN1USP2GAAKMT2AKEAP1
SCHEMBL28289267 0.82 MAPT (0.45) MEN1USP2GAAKMT2AKEAP1
SCHEMBL29131802 0.81 HDAC1 (0.49) MEN1USP2GAAKMT2AKEAP1
SCHEMBL6554490 0.81 F2 (0.47) MEN1USP2GAAKMT2AKEAP1
SCHEMBL4962858 0.80 XDH (0.68) GAAALDH1A1XDHSLC22A12KDM4E
SCHEMBL4852724 0.80 MAPT (0.58) MEN1USP2GAAKMT2ALMNA
SCHEMBL9575745 0.79 LIG1 (0.65) MEN1USP2GAAKMT2AKEAP1
SCHEMBL9575571 0.79 GSK3B (0.51) MEN1USP2GAAKMT2AKEAP1
SCHEMBL9575847 0.79 F2 (0.44) MEN1USP2GAAKMT2AKEAP1
SCHEMBL11757439 0.78 KMT2A (0.58) MEN1USP2GAAKMT2AKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659877-B1 Composition for the treatment of textiles CIBA SC HOLDING AG (CH) 2003-06-04 EP disclosed
US-6398982-B1 FABRIC RINSE FORMULATION INCLUDING HYDROXYARYL 1,3,5-TRIAZINE OR SULFONATED BENZOTRIAZOLE UV ABSORBER; INCREASING SUN PROTECTION FACTOR OF CLOTHING CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-6174854-B1 STABLE, AQUEOUS FABRIC SOFTENING RINSE CONCENTRATE COMPRISING AN ULTRAVIOLET LIGHT ABSORBING 2-N-(2-HYDROXY-3,5-DIALKYL-PHENYL)-2H-BENZOTRIAZOLE AND A TETRAALKYLAMMONIUM COMPOUND; STEROL-FREE CIBA SPECIALTY CHEMICALS CORPORATION 2001-01-16 US disclosed
EP-0659877-A2 Composition for the treatment of textiles CIBA-GEIGY AG (CH) 1995-06-28 EP disclosed