Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.46 |
| ▸ | MMP3 | P08254 | 14/20 | 0.46 |
| ▸ | MMP1 | P03956 | 13/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068205 | 0.93 | MMP3 (0.47) | MMP2MMP3MMP1EPHX2EPHX1 | |
| SCHEMBL7067053 | 0.87 | CNR1 (0.42) | EPHX2CNR1KMT2A | |
| SCHEMBL7067062 | 0.79 | MMP8 (0.43) | MMP1EPHX2CNR1KMT2A | |
| SCHEMBL7068140 | 0.77 | MMP2 (0.51) | MMP2MMP3MMP1EPHX2 | |
| SCHEMBL7068135 | 0.77 | MMP2 (0.51) | MMP2MMP3MMP1EPHX2 | |
| SCHEMBL7069865 | 0.76 | CNR1 (0.41) | EPHX2CNR1KMT2A | |
| SCHEMBL7069327 | 0.74 | MMP3 (0.51) | MMP2MMP3MMP1EPHX2EPHX1 | |
| SCHEMBL7069330 | 0.74 | MMP3 (0.51) | MMP2MMP3MMP1EPHX2EPHX1 | |
| SCHEMBL7066777 | 0.71 | MMP3 (0.46) | MMP2MMP3MMP1EPHX2KMT2A | |
| SCHEMBL27549172 | 0.68 | MMP2 (0.58) | MMP2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | claimed |
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | claimed |
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |