Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.51 |
| ▸ | MMP1 | P03956 | 8/20 | 0.51 |
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069327 | 1.00 | MMP3 (0.51) | MMP3MMP1MMP2EPHX1KMT2A | |
| SCHEMBL5523633 | 0.78 | EPHX1 (0.57) | MMP3MMP1MMP2EPHX1KMT2A | |
| SCHEMBL7068205 | 0.76 | MMP3 (0.47) | MMP3MMP1MMP2EPHX1KMT2A | |
| SCHEMBL27549172 | 0.75 | MMP2 (0.58) | MMP3MMP1MMP2 | |
| SCHEMBL7068133 | 0.74 | MMP2 (0.46) | MMP3MMP1MMP2EPHX2 | |
| SCHEMBL7066782 | 0.74 | MMP2 (0.46) | MMP3MMP1MMP2EPHX1KMT2A | |
| SCHEMBL7355387 | 0.72 | METAP2 (0.62) | MMP3MMP1MMP2EPHX1KMT2A | |
| Hydrochloric Acid SCHEMBL7354348 | 0.71 | METAP2 (0.61) | MMP3MMP1MMP2EPHX1EPHX2 | |
| SCHEMBL7068140 | 0.71 | MMP2 (0.51) | MMP3MMP1MMP2EPHX2 | |
| SCHEMBL7068135 | 0.71 | MMP2 (0.51) | MMP3MMP1MMP2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |